Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965571 | 1.00 | PRMT6 (0.51) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL8088260 | 1.00 | PRMT6 (0.51) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL15983145 | 0.88 | MC4R (0.53) | ALDH1A1SMN1; SMN2TDP1KDM4EGAA | |
| SCHEMBL4547888 | 0.84 | PRMT6 (0.57) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL27046169 | 0.83 | PRMT6 (0.47) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL1619365 | 0.83 | SMN1; SMN2 (0.58) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL1935413 | 0.81 | PRMT6 (0.58) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL19634071 | 0.81 | ALDH1A1 (0.60) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL10178649 | 0.80 | PRMT6 (0.53) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL31010187 | 0.80 | ALDH1A1 (0.63) | PRMT6ALDH1A1SMN1; SMN2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | claimed |
| US-6140510-A | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| CN-1123544-A | Optically active 3-(1-(alkylamino)) alkyl pyrrolidines | UPJOHN CO (US) | 1996-05-29 | — | — | CN | disclosed |