Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330402 | 0.86 | — | — | |
| SCHEMBL8085398 | 0.84 | — | — | |
| SCHEMBL7325525 | 0.84 | ABCB1 (0.39) | — | |
| SCHEMBL7322880 | 0.83 | HTR1A (0.32) | — | |
| SCHEMBL8085025 | 0.83 | AKR1B1 (0.33) | LMNA | |
| SCHEMBL7330998 | 0.83 | KDM4E (0.36) | LMNAMAPK1 | |
| SCHEMBL7333916 | 0.83 | CYP1A2 (0.32) | LMNA | |
| SCHEMBL8076897 | 0.80 | ABCC9 (0.38) | LMNAMAPK1 | |
| SCHEMBL7332017 | 0.80 | ALDH1A1 (0.30) | LMNA | |
| SCHEMBL7326375 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0340718-B1 | Chroman derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0340718-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1989-11-08 | — | — | EP | disclosed |