Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | GAPDH | P04406 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090946 | 0.94 | ACHE (0.58) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL8089112 | 0.86 | ACHE (0.43) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL2494373 | 0.82 | ACHE (0.68) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL2494371 | 0.82 | ACHE (0.68) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL1786850 | 0.82 | TRPA1 (0.58) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL2206650 | 0.82 | MAPT (0.40) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL1786849 | 0.82 | TRPA1 (0.58) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL7077273 | 0.81 | ACHE (0.66) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL11572115 | 0.81 | TRPA1 (0.56) | TRPA1DDAH1GAPDHMAPTACHE | |
| SCHEMBL8985063 | 0.81 | ACHE (0.66) | TRPA1DDAH1GAPDHMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758361-B1 | POLYMERISABLE COMPOSITION AND THE USE THEREOF | NOVARTIS AG (CH) | 2000-11-15 | — | — | EP | disclosed |
| US-5852126-A | Polymerisable composition and the use thereof | NOVARTIS AG (CH) | 1998-12-22 | — | — | US | disclosed |
| EP-0758361-A1 | POLYMERISABLE COMPOSITON AND THE USE THEREOF | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029959-A1 | POLYMERISABLE COMPOSITON AND THE USE THEREOF | CIBA-GEIGY AG (CH) | 1995-11-09 | — | — | WO | disclosed |