Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090946 | 0.88 | ACHE (0.58) | ACHEBACE1MAPTTRPA1DDAH1 | |
| SCHEMBL8089121 | 0.86 | TRPA1 (0.56) | ACHEBACE1MAPTTRPA1DDAH1 | |
| SCHEMBL719805 | 0.82 | — | — | |
| SCHEMBL2545649 | 0.80 | ACHE (0.58) | ACHEBACE1MAPTTRPA1DDAH1 | |
| SCHEMBL1786710 | 0.80 | ACHE (0.44) | ACHEBACE1MAPTTRPA1DDAH1 | |
| SCHEMBL9074798 | 0.80 | CHRM1 (0.36) | ACHEBACE1MAPTALDH1A1CHRM1 | |
| SCHEMBL1786712 | 0.80 | ACHE (0.44) | ACHEBACE1MAPTTRPA1DDAH1 | |
| SCHEMBL1941417 | 0.80 | ACHE (0.58) | ACHEBACE1MAPTTRPA1DDAH1 | |
| Methyl Alcohol SCHEMBL4653215 | 0.78 | ACHE (0.56) | ACHEBACE1MAPTTRPA1DDAH1 | |
| SCHEMBL3230819 | 0.78 | ALDH1A1 (0.36) | ACHEBACE1MAPTALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758361-B1 | POLYMERISABLE COMPOSITION AND THE USE THEREOF | NOVARTIS AG (CH) | 2000-11-15 | — | — | EP | disclosed |
| US-5852126-A | Polymerisable composition and the use thereof | NOVARTIS AG (CH) | 1998-12-22 | — | — | US | disclosed |
| US-4009195-A | FROM 1-ALKENES AND ACRYLIC ACID DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3994958-A | OF 1-ALKENES AND ACRYLIC ACID DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
| US-3968148-A | Copolymers of 1-alkenes and acrylic acid derivatives | ROHM AND HAAS COMPANY (US) | 1976-07-06 | — | — | US | disclosed |