Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201182 | 0.87 | GAA (0.36) | GAAMAPTELANECTSGL3MBTL1 | |
| SCHEMBL19097289 | 0.79 | ATM (0.43) | ALDH1A1CHRM1CHRM2CHRM3ATM | |
| SCHEMBL7841491 | 0.75 | LMNA (0.40) | GAAL3MBTL1POLBALDH1A1CHRM1 | |
| SCHEMBL5255605 | 0.73 | SMN1; SMN2 (0.38) | POLBALDH1A1CHRM1CHRM2CHRM3 | |
| SCHEMBL10949793 | 0.73 | SMN1; SMN2 (0.46) | ELANE | |
| SCHEMBL10142030 | 0.73 | S1PR1 (0.45) | GAAMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL21409408 | 0.71 | POLB (0.35) | MAPTPOLBHPGDCHRM1CHRM2 | |
| SCHEMBL3877432 | 0.71 | DPP4 (0.37) | MAPTPOLBHPGDCHRM1CHRM2 | |
| SCHEMBL4070279 | 0.71 | GAA (0.57) | GAAMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL11597056 | 0.71 | PKM (0.37) | GAAELANECTSGL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |