Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 10/20 | 0.43 |
| ▸ | CTSS | P25774 | 9/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093610 | 0.89 | CTSS (0.55) | CTSKCTSSMMP2MMP3MMP7 | |
| SCHEMBL5155444 | 0.87 | CTSS (0.48) | ITGB3ITGA2BCTSKCTSSMMP2 | |
| SCHEMBL5887534 | 0.80 | CTSS (0.53) | ITGB3ITGA2BCTSKCTSSCTSL | |
| SCHEMBL5887530 | 0.80 | CTSS (0.53) | ITGB3ITGA2BCTSKCTSSCTSL | |
| SCHEMBL6676842 | 0.80 | CTSK (0.57) | CTSKCTSSMMP2MMP3MMP7 | |
| SCHEMBL8093013 | 0.79 | CTSS (0.53) | CTSKCTSSMMP2MMP3MMP7 | |
| SCHEMBL3901262 | 0.78 | ACE (0.62) | ITGB3ITGA2BCTSKCTSSCTSL | |
| SCHEMBL1201951 | 0.78 | ACE (0.62) | ITGB3ITGA2BCTSKCTSSCTSL | |
| SCHEMBL10077582 | 0.78 | CTSS (0.53) | ITGB3ITGA2BCTSKCTSSCTSL | |
| SCHEMBL606689 | 0.78 | ACE (0.62) | ITGB3ITGA2BCTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273835-A1 | NOVEL COMPOUNDS | PROBIODRUG AG (DE) | 2010-10-28 | — | — | US | disclosed |
| US-20100273835-A1 | NOVEL COMPOUNDS | PROBIODRUG AG (DE) | 2010-10-28 | — | — | US | disclosed |
| WO-2009007415-A2 | NOVEL COMPOUNDS | PROBIODRUG AG (DE) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273835-A1 | NOVEL COMPOUNDS | IL6, PREP, PEPD | ITGB3 2622/4885ITGA2B 4071/4885CTSK 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.