Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418148 | 0.80 | ELANE (0.66) | ELANE | |
| SCHEMBL17585016 | 0.80 | ELANE (0.70) | ELANEALDH1A1TDP1PRTN3MAPT | |
| SCHEMBL1398724 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10ALOX15APEX1 | |
| SCHEMBL17295084 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10ALOX15APEX1 | |
| SCHEMBL22369614 | 0.78 | ELANE (0.86) | ELANEPRTN3 | |
| SCHEMBL8518580 | 0.77 | RAB9A (0.61) | ALDH1A1LMNAHSD17B10ALOX15APEX1 | |
| SCHEMBL434768 | 0.77 | CA12 (0.57) | ALDH1A1APEX1RECQLTDP1MAPT | |
| SCHEMBL4639551 | 0.77 | ELANE (1.00) | ELANE | |
| SCHEMBL3955658 | 0.76 | LMNA (0.70) | ALDH1A1LMNAHSD17B10ALOX15APEX1 | |
| SCHEMBL23759975 | 0.75 | ELANE (0.75) | ELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140310-A | ADMINISTERING AN EFFECTIVE AMOUNT OF PHOSPHORUS PRODRUG IN A MAMMAL FOR TREATING A VIRAL INFECTION | DRUG INNOVATION & DESIGN, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-5789608-A | LIPID SOLUBLE; DIFFUSE INTO CELLS AND TISSUE; VIRICIDES, ANTICANCER AGENTS | DRUG INNOVATION AND DESIGN, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5627165-A | ANTIVIRAL AND ANTILEUKEMIA AGENTS | DRUG INNOVATION & DESIGN, INC. (US) | 1997-05-06 | — | — | US | disclosed |