SCHEMBL8089214

SCHEMBL8089214

NC1=CCC(C(=O)O)(c2ccccc2)C=C1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.37
HDAC4 P56524 4/20 0.34
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
HSD11B1 P28845 1/20 0.31
MAOB P27338 1/20 0.31
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21878931 0.89
SCHEMBL27805964 0.87 OPRD1 (0.35) AKR1C1HDAC4OPRM1OPRL1
SCHEMBL347447 0.81 AKR1C1 (0.38) AKR1C1HDAC4LMNAHTTHSD11B1
SCHEMBL2521627 0.80 AKR1C1 (0.37) AKR1C1HDAC4LMNAHTTHSD11B1
SCHEMBL27042598 0.79 HDAC4 (0.37) AKR1C1HDAC4LMNAHTTTDP1
SCHEMBL30661188 0.75 MEN1 (0.38) LMNA
SCHEMBL1477275 0.74 MAOB (0.31) HDAC4MAOBOPRM1OPRL1
SCHEMBL9199935 0.73 EGFR (0.36) TDP1
SCHEMBL28577983 0.72 DHODH (0.37) AKR1C1HDAC4TDP1
SCHEMBL5930802 0.72 PNMT (0.35) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5391651-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1995-02-21 US claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5270405-A Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270404-A Curable compositions of mesogen-containing advanced epoxy resins and curing agents therefor THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
EP-0379057-B1 Mesogenic epoxy compounds DOW CHEMICAL CO (US) 2000-12-06 EP disclosed
EP-0379055-B1 Mesogenic advanced epoxy compounds DOW CHEMICAL CO (US) 1999-11-10 EP disclosed
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP disclosed
EP-0708796-B1 PROCESS FOR PREPARING COMPOSITES BASED ON ORIENTED MESOGENIC THERMOSET RESINS DOW CHEMICAL CO (US) 1998-05-27 EP disclosed
US-5736620-A ENHANCED UNIDIRECTIONAL, MECHANICAL PROPERTIES AT LOWER TEMPERATURE THE DOW CHEMICAL COMPANY (US) 1998-04-07 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
EP-0379057-A2 Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
EP-0379055-A2 Mesogenic advanced epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed