Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27358257 | 0.76 | KDM4E (0.47) | KDM4ETSHRPOLBALDH1A1HTT | |
| SCHEMBL8499717 | 0.76 | KDM4E (0.47) | KDM4ETSHRPOLBALDH1A1HTT | |
| SCHEMBL17844038 | 0.76 | KDM4E (0.47) | KDM4ETSHRPOLBALDH1A1HTT | |
| SCHEMBL353826 | 0.75 | CYP3A4 (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL2269279 | 0.73 | CYP3A4 (0.49) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL5594263 | 0.73 | KDR (0.57) | KDM4ETSHRPOLB | |
| SCHEMBL9808678 | 0.73 | CCR1 (0.47) | KDM4ETSHRALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL21753738 | 0.72 | KDM4E (0.44) | KDM4ETSHRPOLBALDH1A1HTT | |
| SCHEMBL25778550 | 0.71 | KDM4E (0.66) | KDM4ETSHRPOLBALDH1A1HTT | |
| SCHEMBL9372056 | 0.69 | TSHR (0.46) | KDM4ETSHRPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043242-A | TREATING A MAMMAL AFFLICTED WITH A DISEASE BASED ON HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |
| EP-0328024-B1 | Tetramethylpiperidino-s triazines | CIBA GEIGY AG (CH) | 1994-12-28 | — | — | EP | disclosed |
| EP-0249938-B1 | Imidazolesulfonamide derivatives, herbicides and a method for inhibiting growth of undesirable plants | NISSAN CHEMICAL IND LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| CN-1020902-C | IMIDAZOLE DERIVATIVE AND PROCESSES FOR PREPARING SAME | TANAHBE SEIYAKU CO LTD (JP) | 1993-05-26 | — | — | CN | disclosed |
| EP-0270091-B1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION OF THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS OF THERAPEUTIC VALUE, AND INTERMEDIATES FORMED DURING SAID PROCESSES | TANABE SEIYAKU CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-5053417-A | Antiulcer agents | TANABE SEIYAKU CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| US-5002945-A | Antiulcer agents | TANABE SEIYAKU CO. LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| US-4996217-A | Antiulcer agents | TANABE SEIYAKU COMPANY, LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0328024-A1 | Tetramethylpiperidino-s triazines | CIBA-GEIGY AG (CH) | 1989-08-16 | — | — | EP | disclosed |
| US-4830660-A | Imidazolesulfonamide derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| CN-87108111-A | Novel imidazole derivative and preparation method thereof | — | 1988-09-28 | — | — | CN | disclosed |
| EP-0270091-A1 | Imidazole derivatives, processes for the preparation of the same, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments of therapeutic value, and intermediates formed during said processes | TANABE SEIYAKU CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |
| EP-0249938-A2 | Imidazolesulfonamide derivatives, herbicides and a method for inhibiting growth of undesirable plants | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-12-23 | — | — | EP | disclosed |