Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704416 | 0.92 | AGTR2 (0.55) | AGTR2AGTR1 | |
| SCHEMBL8706437 | 0.87 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL8089307 | 0.83 | AGTR2 (0.62) | AGTR2AGTR1 | |
| SCHEMBL8707896 | 0.81 | AGTR1 (0.49) | AGTR2AGTR1 | |
| SCHEMBL8792974 | 0.80 | AGTR2 (0.70) | AGTR2AGTR1 | |
| SCHEMBL8081448 | 0.79 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL8088534 | 0.79 | AGTR2 (0.56) | AGTR2AGTR1 | |
| SCHEMBL8792459 | 0.79 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL8089376 | 0.79 | AGTR1 (0.54) | AGTR2AGTR1 | |
| SCHEMBL8792485 | 0.78 | AGTR1 (0.64) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037349-A | HAVING ANTAGONISTIC PROPERTIES TOWARDS ANGIOTENSIN II CAN BE USED FOR THE TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GMBH (DE) | 2000-03-14 | — | — | US | disclosed |