Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.64 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321188 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2GP6 | |
| SCHEMBL8735381 | 0.91 | AGTR1 (0.68) | AGTR1AGTR2GP6 | |
| SCHEMBL359 | 0.90 | GP6 (0.63) | AGTR1AGTR2GP6 | |
| SCHEMBL8792974 | 0.88 | AGTR2 (0.70) | AGTR1AGTR2 | |
| SCHEMBL8792459 | 0.87 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8719876 | 0.86 | AGTR1 (0.57) | AGTR1AGTR2GP6 | |
| SCHEMBL8326292 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL33 | 0.83 | AGTR1 (0.75) | AGTR1AGTR2GP6 | |
| SCHEMBL9214999 | 0.83 | AGTR1 (0.65) | AGTR1AGTR2GP6 | |
| SCHEMBL8439141 | 0.83 | AGTR1 (0.53) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652869-B1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | LUSO FARMACO INST (IT) | 1997-03-26 | — | — | EP | disclosed |
| US-5538987-A | Imidazole ethers having a II antagonist activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-07-23 | — | — | US | disclosed |
| EP-0652869-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-17 | — | — | EP | disclosed |