SCHEMBL8089442

SCHEMBL8089442

COC=CCc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
NT5E P21589 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
CA2 P00918 4/20 0.33
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
POLB P06746 1/20 0.33
CYP2D6 P10635 1/20 0.33
F13A1 P00488 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22273552 0.83 LMNA (0.37) LMNATDP1ALDH1A1TSHRNT5E
SCHEMBL18637980 0.80 TSHR (0.47) LMNATDP1ALDH1A1TSHRNT5E
SCHEMBL778029 0.77 LMNA (0.43) LMNATDP1ALDH1A1TSHRNT5E
SCHEMBL5032523 0.76 IDO1 (0.45) ALDH1A1KDM4ECA2
SCHEMBL8386014 0.75 LMNA (0.50) LMNATDP1ALDH1A1TSHRNT5E
SCHEMBL5021267 0.74 TP53 (0.37) LMNATDP1ALDH1A1TSHRSMN1; SMN2
SCHEMBL5021265 0.74 AGXT (0.45) TDP1ALDH1A1TSHRSMN1; SMN2CYP1A2
SCHEMBL1784538 0.74 TP53 (0.37) LMNATDP1ALDH1A1TSHRSMN1; SMN2
SCHEMBL1781780 0.74 AGXT (0.45) TDP1ALDH1A1TSHRSMN1; SMN2CYP1A2
SCHEMBL8180716 0.72 LOXL2 (0.56) LMNATDP1ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0766757-B1 ACRYLIC FIBER WITH HIGH OPTICAL BRIGHTNESS MONSANTO CO (US) 2000-12-06 EP disclosed
US-6066687-A A FIBER FORMED FROM AN ACRYLONITRILE POLYMER AND COMPRISING A DELUSTRANT AND AN OPTICAL BRIGHTENER, CHARACTERIZED BY A BRIGHTNESS VALUE OF ATLEAST ABOUT 79 SOLUTIA INC. (US) 2000-05-23 US disclosed
WO-1999005986-A1 IMPROVED DENTAL FLOSS WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1999-02-11 WO disclosed
US-5232647-A Process of making bicomponent acrylic fibers having reversible crimp AMERICAN CYANAMID COMPANY (US) 1993-08-03 US disclosed
US-5130195-A Hydrophilic sulfonated polyacrylonitrile AMERICAN CYANAMID COMPANY (US) 1992-07-14 US disclosed
EP-0490052-A2 Reversible crimp bicomponent acrylic fibers CYTEC TECHNOLOGY CORP. (US) 1992-06-17 EP disclosed
US-4524105-A CONTAINING BLOCK OF POLYVINYL ALCOHOL; DYEABILITY AMERICAN CYANAMID COMPANY (US) 1985-06-18 US disclosed
US-4418176-A Self-crimping acrylic fiber from a melt of two non-compatible polymers AMERICAN CYANAMID COMPANY (US) 1983-11-29 US disclosed
US-4301107-A TWO-STAGE STRETCHING AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4301112-A Process for biaxially oriented acrylonitrile polymer barrier film AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4301104-A DISPERSING TWO POLYMERS WITH DIFFERENT PROPERTIES AMERICAN CYANAMID COMPANY (US) 1981-11-17 US disclosed
US-4296175-A FOR TEXTILES AMERICAN CYANAMID COMPANY (US) 1981-10-20 US disclosed
US-4255532-A A GRAFT POLYMER COMPRISING ACRYLONITRILE, POLYVINYL ALCOHOL, AND AN ACRYLIC ESTER; TEXTILE FIBERS; DYEABILITY AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
EP-0014803-A1 Process for preparing acrylonitrile polymer fiber of hollow or open structure AMERICAN CYANAMID COMPANY (US) 1980-09-03 EP disclosed
US-4205039-A CONTAINING HYDROPHOBIC MONOMERS AND A HYDROPHILIC MOIETY TO FORM A SINGLE PHASE MELT USING A MINIMUM AMOUNT OF WATER AMERICAN CYANAMID COMPANY (US) 1980-05-27 US disclosed
US-4163770-A Melt-spinning acrylonitrile polymer fibers AMERICAN CYANAMID COMPANY (US) 1979-08-07 US disclosed