SCHEMBL22273552

SCHEMBL22273552

CCO/C=C/Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
NT5E P21589 1/20 0.36
F13A1 P00488 1/20 0.36
TGM2 P21980 1/20 0.36
TGM1 P22735 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
CA2 P00918 6/20 0.33
PSIP1 O75475 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
POLB P06746 1/20 0.32
CYP2D6 P10635 1/20 0.32
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089442 0.83 LMNA (0.39) LMNATDP1TSHRALDH1A1NT5E
SCHEMBL18637980 0.78 TSHR (0.47) LMNATDP1TSHRALDH1A1NT5E
SCHEMBL986652 0.75 ALDH1A1 (0.52) TDP1TSHRALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL778029 0.74 LMNA (0.43) LMNATDP1TSHRALDH1A1NT5E
SCHEMBL10433375 0.73 MAOB (0.56) TSHRALDH1A1CA2CA1
SCHEMBL10433374 0.73 MAOB (0.56) TSHRALDH1A1CA2CA1
SCHEMBL8386014 0.73 LMNA (0.50) LMNATDP1TSHRALDH1A1NT5E
SCHEMBL1563242 0.70 CA2 (0.61) LMNATDP1TSHRALDH1A1NT5E
SCHEMBL93796 0.70 CA2 (0.61) LMNATDP1TSHRALDH1A1NT5E
SCHEMBL14582521 0.70 LMNA (0.48) LMNATDP1TSHRALDH1A1NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200237918-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures VANDERBILT UNIVERSITY 2020-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200237918-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures STT3A, STT3B, B3GAT3 LMNA 854/4885TDP1 3944/4885TSHR 2588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.