Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132193 | 0.86 | MRGPRX4 (0.45) | ALDH1A1HPGDS1PR3S1PR1 | |
| SCHEMBL20515885 | 0.85 | TSHR (0.53) | ALDH1A1HPGDTP53TSHR | |
| SCHEMBL8214320 | 0.85 | ALDH1A1 (0.55) | PLA2G2ACNR1CNR2PTPN11ALDH1A1 | |
| SCHEMBL20515855 | 0.84 | MRGPRX4 (0.46) | ALDH1A1HPGD | |
| SCHEMBL28096463 | 0.82 | MAPK1 (0.51) | ALDH1A1HPGD | |
| SCHEMBL9342126 | 0.82 | KDM4E (0.51) | PLA2G2A | |
| SCHEMBL10818687 | 0.81 | CNR1 (0.51) | CNR1CNR2CYP2C9PTPN11ALDH1A1 | |
| SCHEMBL9108912 | 0.80 | MRGPRX4 (0.49) | ALDH1A1HPGD | |
| SCHEMBL6563613 | 0.80 | KDM4E (0.64) | ALDH1A1HPGD | |
| SCHEMBL9111488 | 0.80 | MRGPRX4 (0.44) | ALDH1A1HPGDS1PR3S1PR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |