⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359360 | 0.86 | — | — | |
| SCHEMBL7356015 | 0.84 | DGKA (0.52) | — | |
| SCHEMBL14032355 | 0.84 | TSHR (0.38) | — | |
| SCHEMBL5698805 | 0.82 | DGKA (0.55) | — | |
| SCHEMBL8587852 | 0.82 | DGKA (0.55) | — | |
| SCHEMBL9947473 | 0.82 | DGKA (0.55) | — | |
| SCHEMBL5705163 | 0.82 | DGKA (0.55) | — | |
| SCHEMBL1551559 | 0.79 | — | — | |
| SCHEMBL1712975 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL3629946 | 0.78 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106916236-B | A kind of cyclodextrin-camptothecin supermolecule chemotherapeutics and its preparation and application | 莎穆(上海)生物科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| EP-2189443-B1 | TRICYCLIC AMIDE COMPOUND | RES FOUND ITSUU LAB (JP) | 2013-10-23 | — | — | EP | claimed |
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | claimed |
| US-8795904-B2 | Nonaqueous electrolyte solvents and additives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2014-08-05 | — | — | US | disclosed |
| US-20110281177-A1 | NONAQUEOUS ELECTROLYTE SOLVENTS AND ADDITIVES | US GOVERNMENT AS REPRESENTED BY SECRETARY OF THE ARMY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110281177-A1 | NONAQUEOUS ELECTROLYTE SOLVENTS AND ADDITIVES | US GOVERNMENT AS REPRESENTED BY SECRETARY OF THE ARMY (US) | 2011-11-17 | — | — | US | disclosed |
| EP-0462009-B1 | Cephalosporins having in position 3 a propenyl radical substituted by a quaternary ammonium, their process for preparation, their use as medicaments, compositions containing them and intermediates | HOECHST MARION ROUSSEL INC (FR) | 1998-10-28 | — | — | EP | disclosed |
| EP-0693496-A1 | Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1996-01-24 | — | — | EP | disclosed |
| EP-0315518-B1 | Cephalosporins having in position 3 a substituted vinyl radical, their process for preparation, their application as medicaments, compositions containing them and intermediates | ROUSSEL UCLAF (FR) | 1994-02-16 | — | — | EP | disclosed |
| EP-0282365-B1 | 1-DETHIA-2-THIA-CEPHALOSPORANIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0153229-B1 | 1-DETHIA 2-THIA-CEPHALOSPORANIC ACID DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND THE COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0076528-B1 | OXIME DERIVATIVES OF 3-ALKYLOXY OR 3-ALKYLTHIOMETHYL 7-AMINO-THIAZOLYLACETAMIDO-CEPHALOSPORANIC ACID AND THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |
| EP-0315518-A1 | Cephalosporins having in position 3 a substituted vinyl radical, their process for preparation, their application as medicaments, compositions containing them and intermediates | ROUSSEL-UCLAF (FR) | 1989-05-10 | — | — | EP | disclosed |
| EP-0114128-B1 | 3-AMINO-2-OXO-AZETIDINE DERIVATIVES CONTAINING IN POSITION 1 A NITROGEN HETEROCYCLIC RADICAL, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTICAL AGENTS AND INTERMEDIATES FOR THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1989-03-22 | — | — | EP | disclosed |
| EP-0282365-A1 | 1-Dethia-2-thia-cephalosporanic-acid derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1988-09-14 | — | — | EP | disclosed |
| EP-0213995-A1 | 3-Amino-2-oxo-azetidine derivatives containing in position 1 a nitrogen heterocyclic radical, process for their preparation and their use as therapeutical agents | ROUSSEL-UCLAF (FR) | 1987-03-11 | — | — | EP | disclosed |
| EP-0214029-A1 | 1-Dethia-2-thia cephalosporanic-acid derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1987-03-11 | — | — | EP | disclosed |
| EP-0153229-A2 | 1-Dethia 2-thia-cephalosporanic acid derivatives, process and intermediates for their preparation, their use as therapeutic agents and the compositions containing them | ROUSSEL-UCLAF (FR) | 1985-08-28 | — | — | EP | disclosed |
| EP-0034536-B1 | OXIME DERIVATIVES OF 3-ALKYLOXY- OR 3-ALKYLTHIOMETHYL 7-AMINO-THIAZOLYLACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1984-12-27 | — | — | EP | disclosed |
| EP-0034536-A2 | Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1981-08-26 | — | — | EP | disclosed |