Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089969 | 0.87 | NOTUM (0.38) | SLC6A2SLC6A4SLC6A3ADAM17MAPT | |
| SCHEMBL8090534 | 0.87 | KAT2B (0.48) | MAPTMEN1KMT2A | |
| SCHEMBL8103926 | 0.87 | ALDH1A1 (0.45) | SLC6A2SLC6A4SLC6A3MAPTMEN1 | |
| SCHEMBL8098980 | 0.84 | — | — | |
| SCHEMBL8098716 | 0.83 | NOTUM (0.45) | — | |
| SCHEMBL10733179 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ADAM17MAPT | |
| SCHEMBL8097620 | 0.82 | HSD17B10 (0.39) | NPC1RAB9AHDAC1HDAC8HDAC6 | |
| SCHEMBL8090389 | 0.81 | ALDH1A1 (0.43) | MAPTHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL8090023 | 0.80 | ALDH1A1 (0.33) | MAPTMEN1KMT2A | |
| SCHEMBL10729129 | 0.77 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3ADAM17MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022976-A | Process for the production of 5-hydroxyoxazolidinones | ZENECA LIMITED | 2000-02-08 | — | — | US | disclosed |
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0880510-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028138-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |