Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089747 | 0.87 | SLC6A2 (0.45) | MAPTKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL8099358 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2PKMMAPT | |
| SCHEMBL8090534 | 0.83 | KAT2B (0.48) | ALDH1A1HPGDMAPTPOLBGAA | |
| SCHEMBL8098980 | 0.80 | — | — | |
| SCHEMBL8089969 | 0.80 | NOTUM (0.38) | SMN1; SMN2MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL8097872 | 0.79 | HTT (0.42) | ALDH1A1HPGDSMN1; SMN2PKMPOLB | |
| SCHEMBL8097620 | 0.79 | HSD17B10 (0.39) | ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL8090389 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTGAAGFER | |
| SCHEMBL8098716 | 0.77 | NOTUM (0.45) | — | |
| SCHEMBL8090023 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |