Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090023 | 0.84 | ALDH1A1 (0.33) | HSD17B10ALOX15TSHRALDH1A1ALOX12 | |
| SCHEMBL8097872 | 0.83 | HTT (0.42) | TSHRRAB9ACTSGCMA1ALDH1A1 | |
| SCHEMBL8097433 | 0.82 | MEN1 (0.44) | ALOX15TSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL8089747 | 0.82 | SLC6A2 (0.45) | HDAC1HDAC8HDAC6RAB9ACTSG | |
| SCHEMBL8090389 | 0.82 | ALDH1A1 (0.43) | ALOX15TSHRHDAC1HDAC8HDAC6 | |
| SCHEMBL8090534 | 0.82 | KAT2B (0.48) | HSD17B10ALOX15ALDH1A1HPGDLMNA | |
| SCHEMBL8097654 | 0.81 | ALOX15 (0.43) | HSD17B10ALOX15TSHRCTSGCMA1 | |
| SCHEMBL8089734 | 0.79 | HDAC1 (0.41) | HDAC1HDAC8HDAC6 | |
| SCHEMBL8090371 | 0.79 | POLB (0.44) | RAB9AALDH1A1NPC1MGLLLMNA | |
| SCHEMBL8103926 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |