Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404458 | 0.71 | ADAM17 (0.34) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL3662663 | 0.62 | DPP4 (0.44) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL19412129 | 0.61 | — | — | |
| SCHEMBL11278859 | 0.60 | NOS3 (0.40) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL27689559 | 0.60 | DPP4 (0.44) | KMT2AMEN1KDM4EGAALMNA | |
| SCHEMBL9517115 | 0.60 | MAPT (0.33) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL11018073 | 0.59 | DPP4 (0.60) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL28405609 | 0.57 | MEN1 (0.33) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL19585730 | 0.57 | ADAM17 (0.57) | ALDH1A1L3MBTL1 | |
| SCHEMBL28433212 | 0.57 | SMN1; SMN2 (0.53) | ALDH1A1GAAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |