Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 13/20 | 0.55 |
| ▸ | CCKBR | P32239 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081894 | 0.90 | CCKAR (0.54) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8785301 | 0.76 | CCKAR (0.58) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8089877 | 0.74 | ALDH1A1 (0.39) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8806407 | 0.72 | CCKAR (0.79) | CCKARCCKBR | |
| SCHEMBL8095729 | 0.71 | CCKAR (0.67) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8081918 | 0.71 | CCKBR (0.67) | CCKARCCKBR | |
| SCHEMBL29440045 | 0.71 | CCKAR (1.00) | CCKARCCKBR | |
| SCHEMBL3890199 | 0.71 | CCKAR (1.00) | CCKARCCKBR | |
| SCHEMBL8089860 | 0.71 | CCKAR (0.66) | CCKARCCKBR | |
| SCHEMBL8093408 | 0.71 | ALDH1A1 (0.55) | CCKARCCKBRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096885-A | EXHIBIT AGONIST ACTIVITY FOR CCK-A RECEPTORS THEREBY ENABLING THEM TO MODULATE THE HORMONES GASTRIN AND CHOLECYSTOKININ IN MAMMALS. | GLAXO WELLCOME INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0785944-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011940-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1996-04-25 | — | — | WO | disclosed |