Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | CCKAR | P32238 | 12/20 | 0.54 |
| ▸ | CCKBR | P32239 | 12/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784561 | 1.00 | NPY1R (0.59) | NPY1RCCKARCCKBRXIAPMME | |
| SCHEMBL8784568 | 1.00 | NPY1R (0.59) | NPY1RCCKARCCKBRXIAPMME | |
| SCHEMBL8089978 | 0.80 | CCKBR (0.65) | CCKARCCKBR | |
| SCHEMBL8081904 | 0.79 | CCKBR (0.63) | NPY1RCCKARCCKBR | |
| SCHEMBL8081898 | 0.78 | ALDH1A1 (0.45) | CCKARCCKBRMMEACE | |
| SCHEMBL8095851 | 0.78 | ACE (0.46) | CCKARCCKBRXIAPMMEACE | |
| SCHEMBL8089993 | 0.78 | ACE (0.46) | CCKARCCKBRXIAPMMEACE | |
| SCHEMBL8089886 | 0.76 | ALDH1A1 (0.43) | CCKARCCKBRACE | |
| SCHEMBL8088994 | 0.74 | CCKAR (0.45) | CCKARCCKBRXIAPMMEACE | |
| SCHEMBL8089882 | 0.74 | CCKAR (0.62) | CCKARCCKBRMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096885-A | EXHIBIT AGONIST ACTIVITY FOR CCK-A RECEPTORS THEREBY ENABLING THEM TO MODULATE THE HORMONES GASTRIN AND CHOLECYSTOKININ IN MAMMALS. | GLAXO WELLCOME INC. (US) | 2000-08-01 | — | — | US | claimed |
| US-6096885-A | EXHIBIT AGONIST ACTIVITY FOR CCK-A RECEPTORS THEREBY ENABLING THEM TO MODULATE THE HORMONES GASTRIN AND CHOLECYSTOKININ IN MAMMALS. | GLAXO WELLCOME INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0785944-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011940-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1996-04-25 | — | — | WO | disclosed |