Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778182 | 0.79 | CYP2C19 (0.41) | CYP2C19SMN1; SMN2MTNR1AMTNR1BATM | |
| SCHEMBL4711438 | 0.78 | CYP2C19 (0.40) | CYP2C19SMN1; SMN2MTNR1AMTNR1BATM | |
| SCHEMBL27722724 | 0.77 | CYP2C19 (0.37) | CYP2C19SMN1; SMN2MTNR1AMTNR1BATM | |
| SCHEMBL16087756 | 0.76 | CYP2C19 (0.43) | CYP2C19SMN1; SMN2MTNR1AMTNR1BGLA | |
| SCHEMBL4633428 | 0.76 | MTNR1A (0.46) | CYP2C19SMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL7600323 | 0.76 | CYP2C19 (0.39) | CYP2C19SMN1; SMN2MTNR1AMTNR1BATM | |
| SCHEMBL27816063 | 0.74 | SLC6A4 (0.50) | CYP2C19SMN1; SMN2RAB9AKDM4ESLC6A4 | |
| SCHEMBL11802140 | 0.74 | MTNR1A (0.39) | MTNR1AMTNR1BPOLBSLC6A4PPARG | |
| SCHEMBL821667 | 0.73 | CYP2C19 (0.41) | CYP2C19SMN1; SMN2MTNR1AMTNR1BGLA | |
| SCHEMBL1811046 | 0.73 | CYP2C19 (0.41) | CYP2C19SMN1; SMN2MTNR1AMTNR1BGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020446-A | Curable composition | KANEKA CORPORATION (JP) | 2000-02-01 | — | — | US | disclosed |