Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083449 | 0.91 | EPHX2 (0.41) | MMP8SPHK1F2EPHX2 | |
| SCHEMBL8083486 | 0.90 | EPHX2 (0.41) | MMP8SPHK1F2EPHX2EPHX1 | |
| SCHEMBL8096021 | 0.89 | CYP1A2 (0.37) | MMP8SPHK1 | |
| SCHEMBL8089921 | 0.89 | MMP8 (0.48) | MMP8SPHK1CYP3A4CYP2C19F2 | |
| SCHEMBL8083551 | 0.88 | EPHX2 (0.41) | MMP8SPHK1F2EPHX2 | |
| SCHEMBL8083492 | 0.87 | MMP8 (0.45) | MMP8SPHK1CYP3A4CYP2C19EPHX2 | |
| SCHEMBL8083610 | 0.87 | MMP8 (0.54) | MMP8SPHK1CYP2C19EPHX2L3MBTL1 | |
| SCHEMBL8091411 | 0.86 | MMP8 (0.44) | MMP8SPHK1CYP3A4CYP2C19EPHX2 | |
| SCHEMBL8095058 | 0.86 | SPHK1 (0.43) | MMP8SPHK1F2EPHX2 | |
| SCHEMBL8091477 | 0.83 | TBXA2R (0.40) | F2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |