Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089916 | 0.83 | MMP8 (0.44) | EPHX2F2 | |
| SCHEMBL8083449 | 0.82 | EPHX2 (0.41) | EPHX2TPSAB1F2 | |
| SCHEMBL8083486 | 0.81 | EPHX2 (0.41) | EPHX2TPSAB1F2 | |
| SCHEMBL8083551 | 0.80 | EPHX2 (0.41) | EPHX2TPSAB1CA1CA2CA12 | |
| SCHEMBL7444786 | 0.80 | ALDH1A1 (0.34) | TBXA2REPHX2USP2CAPN1ALDH1A1 | |
| SCHEMBL8083888 | 0.79 | MMP8 (0.33) | SMN1; SMN2KDM4EHTTF2 | |
| SCHEMBL8092142 | 0.78 | ALDH1A1 (0.48) | EPHX2ALDH1A1 | |
| SCHEMBL8095058 | 0.78 | SPHK1 (0.43) | EPHX2TPSAB1CA1CA2CA12 | |
| SCHEMBL7444776 | 0.77 | CAPN1 (0.35) | TBXA2REPHX2USP2CAPN1TPSAB1 | |
| SCHEMBL8096021 | 0.77 | CYP1A2 (0.37) | TPSAB1ALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |