Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLF10 | Q13118 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435720 | 0.80 | PMP22 (0.34) | HIF1APMP22LMNA | |
| SCHEMBL594098 | 0.67 | ADRB2 (0.44) | KLF10ADRB2HIF1ACYP1A2CYP2D6 | |
| SCHEMBL30169480 | 0.67 | ADRB2 (0.44) | KLF10ADRB2HIF1ACYP1A2CYP2D6 | |
| SCHEMBL28218010 | 0.66 | IDO1 (0.44) | KLF10TSHRADRB1IDO1TDP1 | |
| SCHEMBL2639710 | 0.65 | KDM4E (0.40) | TDP1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL28341725 | 0.63 | IDO1 (0.42) | CYP1A2ADRB1IDO1TDP1ALDH1A1 | |
| SCHEMBL28583804 | 0.63 | IDO1 (0.35) | IDO1 | |
| SCHEMBL35629 | 0.63 | KDM4E (0.50) | ADRB2HIF1ACYP1A2CYP2D6TSHR | |
| SCHEMBL29366321 | 0.63 | KDM4E (0.50) | ADRB2HIF1ACYP1A2CYP2D6TSHR | |
| SCHEMBL29435088 | 0.62 | ALDH1A1 (0.39) | KLF10HIF1ACYP1A2TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056740-A1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ENRICHED (R)- OR (S)-ALBUTEROL | Fine Chemicals Corporation (Proprietary) Limited (ZA) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042460-A9 | PROCESS FOR THE PRODUCTION OF OPTICALLY ENRICHED (R)- OR (S)-ALBUTEROL | FINE CHEMICALS CORP PROPRIETAR (ZA) | 2000-03-02 | — | — | WO | disclosed |
| WO-1999042460-A1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ENRICHED (R)- OR (S)-ALBUTEROL | FINE CHEMICALS CORPORATION (PROPRIETARY) LIMITED (ZA) | 1999-08-26 | — | — | WO | disclosed |
| EP-0695178-A1 | MANAGEMENT OF CHOLELITHIASIS WITH BETA-2-AGONISTS | WRIGHT, George Henry (GB) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994025014-A1 | MANAGEMENT OF CHOLELITHIASIS WITH BETA-2-AGONISTS | WRIGHT GEORGE HENRY (GB) | 1994-11-10 | — | — | WO | disclosed |