Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089924 | 0.80 | KLF10 (0.34) | PMP22LMNAHIF1A | |
| Alcohol SCHEMBL17337935 | 0.74 | LMNA (0.34) | PMP22LMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL30254390 | 0.71 | PMP22 (0.40) | PMP22LMNAHPGDHIF1AHSD17B10 | |
| Water SCHEMBL28944323 | 0.70 | PMP22 (0.39) | PMP22LMNAHPGDHIF1AHSD17B10 | |
| Sulfuric Acid SCHEMBL21825446 | 0.65 | PMP22 (0.50) | PMP22CA1CA2CA9LMNA | |
| Sulfuric Acid SCHEMBL2524101 | 0.65 | PMP22 (0.50) | PMP22CA1CA2CA9LMNA | |
| SCHEMBL5075684 | 0.61 | CA1 (0.38) | PMP22CA12CA1CA2CA7 | |
| SCHEMBL20838237 | 0.60 | APP (0.54) | PMP22CA1CA2LMNAHIF1A | |
| SCHEMBL594098 | 0.59 | ADRB2 (0.44) | PMP22LMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL30169480 | 0.59 | ADRB2 (0.44) | PMP22LMNAHPGDHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3155128-A2 | METHODS FOR CHARACTERIZING ALTERNATIVELY OR ABERRANTLY SPLICED MRNA ISOFORMS | Erasmus University Medical Center Rotterdam (NL) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015190921-A2 | METHODS FOR CHARACTERIZING ALTERNATIVELY OR ABERRANTLY SPLICED MRNA ISOFORMS | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2015-12-17 | — | — | WO | disclosed |
| EP-1613266-A4 | METHODS OF TREATING PAIN AND COMPOSITIONS FOR USE THEREFOR | THERAQUEST BIOSCIENCES LLC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1613266-A2 | METHODS OF TREATING PAIN AND COMPOSITIONS FOR USE THEREFOR | Theraquest Biosciences, LLC (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091540-A2 | METHODS OF TREATING PAIN AND COMPOSITIONS FOR USE THEREFOR | THERAQUEST BIOSCIENCES, LLC (US) | 2004-10-28 | — | — | WO | disclosed |