Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090035 | 0.91 | SMN1; SMN2 (0.54) | CYP1A2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8076747 | 0.89 | CYP1A2 (0.55) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8076711 | 0.88 | MAPT (0.51) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8084665 | 0.88 | CYP1A2 (0.57) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8084754 | 0.85 | CYP1A2 (0.49) | CYP1A2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8084106 | 0.81 | NPC1 (0.50) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8084757 | 0.81 | ALDH1A1 (0.49) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8088268 | 0.81 | HSD17B10 (0.50) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8084075 | 0.80 | NR4A2 (0.52) | CYP1A2SMN1; SMN2 | |
| SCHEMBL8089846 | 0.78 | ALDH1A1 (0.53) | CYP1A2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |