Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084078 | 0.91 | CYP1A2 (0.58) | CYP1A2RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8089979 | 0.85 | CYP1A2 (0.51) | CYP1A2RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8076758 | 0.85 | CYP1A2 (0.47) | CYP1A2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL8076711 | 0.84 | MAPT (0.51) | CYP1A2RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8084118 | 0.84 | THRA (0.52) | CYP1A2RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8088063 | 0.78 | CYP1A2 (0.46) | CYP1A2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL8090035 | 0.77 | SMN1; SMN2 (0.54) | CYP1A2RAB9AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL8076747 | 0.77 | CYP1A2 (0.55) | CYP1A2RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8084075 | 0.76 | NR4A2 (0.52) | CYP1A2SMN1; SMN2MAOB | |
| SCHEMBL8084665 | 0.76 | CYP1A2 (0.57) | CYP1A2RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |