Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.68 |
| ▸ | DRD3 | P35462 | 11/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8086718 | 0.99 | DRD2 (0.67) | DRD2DRD3HRH3SLC6A2SLC6A4 | |
| SCHEMBL8086622 | 0.97 | DRD2 (0.69) | DRD2DRD3HRH3SLC6A2SLC6A4 | |
| SCHEMBL8086604 | 0.95 | DRD2 (0.61) | DRD2DRD3HRH3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8078633 | 0.94 | DRD2 (0.61) | DRD2DRD3HRH3SLC6A2SLC6A4 | |
| SCHEMBL4295620 | 0.81 | HRH3 (1.00) | HRH3 | |
| SCHEMBL8086599 | 0.81 | DRD3 (1.00) | DRD2DRD3HRH3SLC6A2SLC6A4 | |
| SCHEMBL3616642 | 0.80 | DRD2 (0.72) | DRD2DRD3SLC6A2SLC6A4LMNA | |
| SCHEMBL246381 | 0.80 | LMNA (0.76) | DRD2DRD3SLC6A2SLC6A4LMNA | |
| SCHEMBL8086583 | 0.79 | DRD2 (1.00) | DRD2DRD3HRH3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11846622 | 0.78 | LMNA (0.93) | DRD2DRD3SLC6A2SLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103724-A | EXHIBIT MAINLY ANTIPSYCHOTIC EFFECTS, E.G., SCHIZOPHRENIA, ORGANIC MENTAL DISORDERS, AFFECTIVE DISORDERS, ANXIETY, PERSONALITY DISORDERS; NEUROLEPTIC ACTIVITIY; ATYPICAL ANTIPSYCHOTICS, COGNITION ACTIVATORS, ANTIDEPRESSANTS; | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2000-08-15 | — | — | US | disclosed |