Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.76 |
| ▸ | HTR2A | P28223 | 2/20 | 0.71 |
| ▸ | HTR7 | P34969 | 2/20 | 0.71 |
| ▸ | DRD2 | P14416 | 3/20 | 0.71 |
| ▸ | DRD3 | P35462 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11846622 | 0.90 | LMNA (0.93) | LMNASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| Dimetholizine SCHEMBL2110772 | 0.87 | DRD2 (0.76) | SLC6A2SLC6A4HTR2AHTR7DRD2 | |
| SCHEMBL6526368 | 0.87 | DRD2 (0.85) | SLC6A2SLC6A4ALDH1A1HTR2AHTR7 | |
| SCHEMBL30206503 | 0.86 | DRD2 (0.78) | LMNASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL1255253 | 0.86 | DRD2 (0.78) | LMNASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8980706 | 0.85 | DRD2 (0.76) | LMNAALDH1A1SMN1; SMN2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL11651993 | 0.85 | DRD2 (0.76) | LMNAALDH1A1SMN1; SMN2HTR2AHTR7 | |
| SCHEMBL3411899 | 0.84 | SLC6A2 (0.76) | LMNASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL8121554 | 0.83 | HTR1A (0.77) | LMNASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL12642679 | 0.83 | LMNA (0.67) | LMNASLC6A2SLC6A4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003418-A2 | FUNCTIONALLY SELECTIVE LIGANDS OF DOPAMINE D2 RECEPTORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-01-05 | — | — | WO | claimed |