Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531757 | 0.79 | KMT2A (0.35) | KMT2AKDM4EALDH1A1HTR2AATM | |
| SCHEMBL10969072 | 0.78 | TSHR (0.34) | KMT2AKDM4EMEN1LMNACASP1 | |
| SCHEMBL7819515 | 0.77 | HTR2A (0.39) | COMTKDM4ELMNAHTR2AHRH1 | |
| SCHEMBL7823808 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1LMNA | |
| SCHEMBL8090075 | 0.76 | TSHR (0.39) | KMT2AKDM4EALDH1A1ATM | |
| SCHEMBL9384051 | 0.76 | DPP4 (0.39) | KMT2AATM | |
| SCHEMBL8090152 | 0.76 | KMT2A (0.33) | KMT2AKDM4EALDH1A1ATM | |
| SCHEMBL9090443 | 0.76 | SMN1; SMN2 (0.46) | KDM4EALDH1A1LMNAAOC3 | |
| SCHEMBL9090435 | 0.76 | CES2 (0.33) | KMT2AKDM4EALDH1A1LMNAATM | |
| Hydrochloric Acid SCHEMBL9985742 | 0.74 | DPP4 (0.38) | KMT2AALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |