Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095188 | 0.98 | MMP8 (0.39) | MMP8HPGDSLC6A4ATML3MBTL1 | |
| SCHEMBL8091670 | 0.97 | MMP8 (0.38) | MMP8HPGDSLC6A4ATML3MBTL1 | |
| SCHEMBL8090153 | 0.93 | MMP8 (0.40) | MMP8HPGDSLC6A4ATML3MBTL1 | |
| SCHEMBL8095182 | 0.91 | MMP8 (0.40) | MMP8HPGDSLC6A4ATML3MBTL1 | |
| SCHEMBL8091668 | 0.90 | MMP8 (0.39) | MMP8HPGDSLC6A4ATML3MBTL1 | |
| SCHEMBL8095467 | 0.88 | CYP3A4 (0.38) | MMP8HPGDCYP1A2TSHRCYP2C19 | |
| SCHEMBL8091588 | 0.88 | MC4R (0.38) | METAP2 | |
| SCHEMBL8091532 | 0.88 | MMP8 (0.36) | MMP8HPGDATML3MBTL1MAPT | |
| SCHEMBL8098091 | 0.87 | MMP8 (0.43) | MMP8HPGDL3MBTL1CYP2D6CYP2C9 | |
| SCHEMBL8095158 | 0.85 | MMP8 (0.36) | MMP8HPGDATML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |