Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.38 |
| ▸ | MC3R | P41968 | 4/20 | 0.38 |
| ▸ | MC5R | P33032 | 3/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 3/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091583 | 0.94 | MC4R (0.39) | MC4RMC3RMC5RMETAP2METAP1 | |
| SCHEMBL8095188 | 0.89 | MMP8 (0.39) | METAP2MMP1ERCC1ERCC4 | |
| SCHEMBL8091670 | 0.89 | MMP8 (0.38) | MMP1ERCC1ERCC4 | |
| SCHEMBL8090156 | 0.88 | MMP8 (0.39) | METAP2 | |
| SCHEMBL8083579 | 0.84 | ALDH1A1 (0.46) | — | |
| SCHEMBL8095182 | 0.82 | MMP8 (0.40) | METAP2MMP1 | |
| SCHEMBL8095467 | 0.82 | CYP3A4 (0.38) | MMP1 | |
| SCHEMBL8091668 | 0.82 | MMP8 (0.39) | MMP1ERCC1ERCC4 | |
| SCHEMBL8095293 | 0.81 | CCR2 (0.40) | — | |
| SCHEMBL8098091 | 0.81 | MMP8 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |