Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 4/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095182 | 0.99 | MMP8 (0.40) | MMP8SLC6A4ATMMMP1HPGD | |
| SCHEMBL8090153 | 0.97 | MMP8 (0.40) | MMP8SLC6A4ATMHPGDALDH1A1 | |
| SCHEMBL8091670 | 0.93 | MMP8 (0.38) | MMP8SLC6A4ATMMMP1HPGD | |
| SCHEMBL8095188 | 0.92 | MMP8 (0.39) | MMP8SLC6A4ATMMMP1HPGD | |
| SCHEMBL8090156 | 0.90 | MMP8 (0.39) | MMP8SLC6A4ATMHPGDL3MBTL1 | |
| SCHEMBL8095466 | 0.89 | CYP2C19 (0.39) | MMP8MMP1ALDH1A1EPHX1 | |
| SCHEMBL8091583 | 0.88 | MC4R (0.39) | MMP1ERCC1ERCC4 | |
| SCHEMBL8098087 | 0.88 | MMP8 (0.44) | MMP8HPGDALDH1A1L3MBTL1 | |
| SCHEMBL8091524 | 0.88 | F2 (0.37) | MMP8ATMMMP1HPGDALDH1A1 | |
| SCHEMBL8095146 | 0.86 | F2 (0.37) | MMP8ATMHPGDEPHX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |