Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 13/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076917 | 0.87 | ABCC9 (0.38) | ABCC9MALT1ABCB1NSD2CASP3 | |
| SCHEMBL7268194 | 0.87 | ABCC9 (0.36) | ABCC9MALT1ABCB1NSD2CASP3 | |
| SCHEMBL7277508 | 0.86 | ABCC9 (0.34) | ABCC9MALT1ABCB1 | |
| SCHEMBL8090777 | 0.85 | PDE4A (0.38) | ABCC9MALT1ICMT | |
| SCHEMBL8076916 | 0.85 | ABCC9 (0.38) | ABCC9MALT1ABCB1MIF | |
| SCHEMBL8077117 | 0.85 | ABCC9 (0.36) | ABCC9MALT1ABCB1 | |
| SCHEMBL8076882 | 0.84 | ABCC9 (0.37) | ABCC9MALT1ABCB1 | |
| SCHEMBL7267575 | 0.84 | ABCC9 (0.37) | ABCC9MALT1ABCB1NSD2CASP3 | |
| SCHEMBL8090107 | 0.83 | ABCC9 (0.35) | ABCC9MALT1ABCB1MIFNSD2 | |
| SCHEMBL8088855 | 0.83 | ABCC9 (0.35) | ABCC9MALT1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |