SCHEMBL8090516

SCHEMBL8090516

CC(C)NC(=O)OC1SC(c2cccc(Cl)c2)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.54
ALDH1A1 P00352 2/20 0.54
MAPT P10636 2/20 0.54
TSHR P16473 1/20 0.54
ALOX15 P16050 2/20 0.36
KCNA3 P22001 1/20 0.35
TP53 P04637 4/20 0.35
GAA P10253 2/20 0.35
HTT P42858 1/20 0.35
MDM2 Q00987 3/20 0.33
POLB P06746 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC6A3 Q01959 1/20 0.33
MEN1 O00255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
OGG1 O15527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8098673 0.84 ALDH1A1 (0.54) HPGDALDH1A1MAPTTSHRTP53
SCHEMBL8098538 0.84 ALDH1A1 (0.36) HPGDALDH1A1MAPTTSHR
SCHEMBL8106100 0.72 NPSR1 (0.43) HPGDALDH1A1MAPTTSHRHTT
SCHEMBL8090390 0.71 ALDH1A1 (0.68) HPGDALDH1A1MAPTTSHRTP53
SCHEMBL8098463 0.71 ALDH1A1 (0.38) HPGDALDH1A1MAPTTSHR
SCHEMBL8096918 0.71 ALDH1A1 (0.38) HPGDALDH1A1MAPTTSHRHTT
SCHEMBL8090125 0.71 GUSB (0.44) HPGDALDH1A1MAPTTSHRHTT
SCHEMBL8097455 0.70 ALDH1A1 (0.40) HPGDALDH1A1MAPTTSHRTP53
SCHEMBL8097010 0.70 HPGD (0.37) HPGDALDH1A1MAPTTSHRALOX15
SCHEMBL8097655 0.70 ALDH1A1 (0.70) HPGDALDH1A1MAPTTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed