SCHEMBL8097655

SCHEMBL8097655

O=C1NC(c2cccc(Cl)c2)SC1Cl

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.70
MAPT P10636 2/20 0.70
HPGD P15428 2/20 0.70
TSHR P16473 1/20 0.70
SLC6A3 Q01959 7/20 0.44
GAA P10253 3/20 0.43
TP53 P04637 1/20 0.43
MDM2 Q00987 1/20 0.43
SLC6A2 P23975 4/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MCL1 Q07820 1/20 0.40
SLC6A4 P31645 1/20 0.39
GID4 Q8IVV7 1/20 0.38
HTT P42858 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.36
PGR P06401 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8090390 0.83 ALDH1A1 (0.68) ALDH1A1MAPTHPGDTSHRSLC6A3
SCHEMBL8096940 0.83 ALDH1A1 (0.49) ALDH1A1MAPTHPGDTSHRMEN1
SCHEMBL8097793 0.83 ALDH1A1 (0.52) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL8090455 0.83 ALDH1A1 (0.49) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL8089623 0.83 ALDH1A1 (0.49) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL8089861 0.79 ALDH1A1 (0.49) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL8096948 0.79 PBRM1 (0.46) ALDH1A1MAPTHPGDTSHRHTT
SCHEMBL8099399 0.79 MAPT (0.49) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL8103622 0.79 ALDH1A1 (0.46) ALDH1A1MAPTHPGDTSHRSLC6A3
SCHEMBL8099137 0.79 ALDH1A1 (0.46) ALDH1A1MAPTHPGDTSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed