Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276973 | 0.91 | F10 (0.33) | F10 | |
| SCHEMBL8085330 | 0.90 | F10 (0.40) | F10 | |
| SCHEMBL7277331 | 0.81 | F10 (0.40) | F10 | |
| SCHEMBL8088448 | 0.81 | RARA (0.32) | F10 | |
| SCHEMBL8084378 | 0.79 | ATM (0.32) | — | |
| SCHEMBL8090591 | 0.79 | F10 (0.33) | F10 | |
| SCHEMBL8084382 | 0.78 | RARA (0.32) | F10 | |
| SCHEMBL8090592 | 0.78 | RXFP1 (0.32) | — | |
| SCHEMBL8088443 | 0.77 | MAOB (0.38) | F10 | |
| SCHEMBL8090551 | 0.77 | RARA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |