Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27908241 | 0.79 | ALDH1A1 (0.39) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| SCHEMBL10663619 | 0.79 | KEAP1 (0.42) | CYP3A4KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL183903 | 0.77 | ALDH1A1 (0.43) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| SCHEMBL27841017 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| Benzene SCHEMBL28947691 | 0.75 | TDP1 (0.44) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| Iodide SCHEMBL27949560 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL8629651 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| SCHEMBL11076120 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| Water SCHEMBL8773033 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRRECQLKEAP1NFE2L2 | |
| SCHEMBL27764997 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRRECQLKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044209-A1 | PROCESS FOR THE PREPARATION OF 6-O-METHYL ERYTHROMYCIN A USING 9-HYDROXY ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999031114-A1 | PROCESS FOR THE PREPARATION OF 6-O-METHYL ERYTHROMYCIN A USING 9-HYDROXY ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-24 | — | — | WO | disclosed |