Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090712 | 1.00 | MAOB (0.38) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL8090989 | 0.79 | MAOB (0.44) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL8090990 | 0.79 | MAOB (0.44) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL2045920 | 0.77 | MAOB (0.50) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL2045922 | 0.77 | MAOB (0.50) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL27702192 | 0.76 | RELA (0.41) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL5903133 | 0.69 | MAOB (0.46) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL3627502 | 0.69 | MAOB (0.46) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL5903130 | 0.69 | MAOB (0.46) | MAOBMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL3627505 | 0.69 | MAOB (0.46) | MAOBMEN1KMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054014-A2 | Method for the preparation of organosilicon compounds and the organosilicon compounds prepared thereby | DOW CORNING CORPORATION (US) | 2000-11-22 | — | — | EP | disclosed |
| US-5998649-A | Organosilicon compounds and method for preparation | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1999-12-07 | — | — | US | disclosed |