SCHEMBL2045922

SCHEMBL2045922

Cl[Si](Cl)(Cl)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
GLA P06280 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 4/20 0.42
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
TRPA1 O75762 1/20 0.42
ALOX5 P09917 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
MAPT P10636 2/20 0.41
RECQL P46063 2/20 0.41
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045920 1.00 MAOB (0.50) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3950302 0.86 AHR (0.35) MAOBMEN1KMT2AALDH1A1MAPK1
SCHEMBL8090989 0.83 MAOB (0.44) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL8090990 0.83 MAOB (0.44) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3949053 0.82 NFE2L2 (0.41) MAOBNFE2L2CYP19A1MAOAMAPT
SCHEMBL5903133 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3627502 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL5903130 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3627505 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL27702192 0.80 RELA (0.41) MAOBMEN1KMT2ACYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777857-B Manufacturing method of low-viscosity high-performance environment-friendly silane modified polyether waterproof coating 江苏瑞洋安泰新材料科技有限公司 2024-08-13 CN claimed
CN-117777857-A Manufacturing method of low-viscosity high-performance environment-friendly silane modified polyether waterproof coating 江苏瑞洋安泰新材料科技有限公司 2024-03-29 CN claimed
CN-108660813-A A kind of formaldehyde-free color fixing agent and preparation method thereof 曾文华 2018-10-16 CN claimed
CN-102604108-B Organic silicon binding agent and special silicon-boron-carbon-nitrogen polymer thereof CHINESE ACAD INST CHEMISTRY 2013-11-06 CN claimed
CN-102604108-A Organic silicon binding agent and special silicon-boron-carbon-nitrogen polymer thereof CHINESE ACAD INST CHEMISTRY 2012-07-25 CN claimed
EP-0436844-B1 High purity hydroxy-terminated phenyl ladder polysiloxane and method for producing the same MITSUBISHI ELECTRIC CORP (JP) 1995-10-18 EP claimed
US-5179185-A By hydrolysis of trichlorosilane mixtures; protective films; insulating film in semiconducdtor production MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1993-01-12 US claimed
EP-0436844-A2 High purity hydroxy-terminated phenyl ladder polysiloxane and method for producing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1991-07-17 EP claimed
CN-117777857-B Manufacturing method of low-viscosity high-performance environment-friendly silane modified polyether waterproof coating 江苏瑞洋安泰新材料科技有限公司 2024-08-13 CN disclosed
CN-117777857-A Manufacturing method of low-viscosity high-performance environment-friendly silane modified polyether waterproof coating 江苏瑞洋安泰新材料科技有限公司 2024-03-29 CN disclosed
CN-104974184-B preparation of silazane Compounds 信越化学工业株式会社 2019-12-06 CN disclosed
CN-108865303-A A kind of slurries additive agent and preparation method thereof containing sulfonic acid group 曾来英 2018-11-23 CN disclosed
CN-108660813-A A kind of formaldehyde-free color fixing agent and preparation method thereof 曾文华 2018-10-16 CN disclosed
EP-2930177-B1 PREPARATION OF SILAZANE COMPOUND SHINETSU CHEMICAL CO (JP) 2018-04-25 EP disclosed
US-4894398-A HYROXYLAMINES AS STORAGE STABILIZERS IN OXYGEN-IMPERVIOUS CONTAINERS DOW CORNING CORPORATION (US) 1990-01-16 US disclosed
EP-0317211-A2 Method for stabilizing unsaturated organosilicone compositions DOW CORNING CORPORATION (US) 1989-05-24 EP disclosed
US-4798889-A HYDROXYLAMINE, POLYMERIZATION INHIBITION DOW CORNING CORPORATION (US) 1989-01-17 US disclosed
US-4447633-A NON-AROMATIC CARBON TO CARBON PI BONDS NORTH DAKOTA STATE UNIVERSITY (US) 1984-05-08 US disclosed
US-4153765-A Curable composition containing EPM or EPDM interpolymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1979-05-08 US disclosed
US-4028483-A EPDM interpolymers formed with unsaturated organosilanes COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1977-06-07 US disclosed