SCHEMBL2045920

SCHEMBL2045920

Cl[Si](Cl)(Cl)/C=C/c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
GLA P06280 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 4/20 0.42
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
TRPA1 O75762 1/20 0.42
ALOX5 P09917 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
MAPT P10636 2/20 0.41
RECQL P46063 2/20 0.41
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045922 1.00 MAOB (0.50) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3950302 0.86 AHR (0.35) MAOBMEN1KMT2AALDH1A1MAPK1
SCHEMBL8090989 0.83 MAOB (0.44) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL8090990 0.83 MAOB (0.44) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3949053 0.82 NFE2L2 (0.41) MAOBNFE2L2CYP19A1MAOAMAPT
SCHEMBL5903133 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3627502 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL5903130 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL3627505 0.80 MAOB (0.46) MAOBMEN1KMT2ACYP11B1CYP11B2
SCHEMBL27702192 0.80 RELA (0.41) MAOBMEN1KMT2ACYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436844-B1 High purity hydroxy-terminated phenyl ladder polysiloxane and method for producing the same MITSUBISHI ELECTRIC CORP (JP) 1995-10-18 EP claimed
CN-104974184-B preparation of silazane Compounds 信越化学工业株式会社 2019-12-06 CN disclosed
EP-2930177-B1 PREPARATION OF SILAZANE COMPOUND SHINETSU CHEMICAL CO (JP) 2018-04-25 EP disclosed
US-9416147-B2 Preparation of silazane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-16 US disclosed
EP-2930177-A1 Preparation of silazane compound Shin-Etsu Chemical Co., Ltd. (JP) 2015-10-14 EP disclosed
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-08 US disclosed
US-8742104-B2 Saturated N-heterocyclic carbene-ligand metal complex derivatives, preparing method thereof, and preparing method of silane compound by hydrosilylation reaction using the same as catalyst KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-06-03 US disclosed
US-20130158148-A1 PHOTOSENSITIVE SILICONE RESIN COMPOSITION ASAHI KASEI E-MATERIALS CORPORATION (JP) 2013-06-20 US disclosed
EP-2604644-A1 PHOTOSENSITIVE SILICONE RESIN COMPOSITION Asahi Kasei E-Materials Corporation (JP) 2013-06-19 EP disclosed
US-7964685-B2 Polymerizable composition ZEON CORPORATION (JP) 2011-06-21 US disclosed
EP-1589054-A1 POLYMERIZABLE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIALS Zeon Corporation (JP) 2005-10-26 EP disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed
EP-0317211-B1 Method for stabilizing unsaturated organosilicone compositions DOW CORNING (US) 1994-05-11 EP disclosed
US-4912239-A Using a hydroxylamine compound DOW CORNING CORPORATION (US) 1990-03-27 US disclosed
US-4894398-A HYROXYLAMINES AS STORAGE STABILIZERS IN OXYGEN-IMPERVIOUS CONTAINERS DOW CORNING CORPORATION (US) 1990-01-16 US disclosed
EP-0317211-A2 Method for stabilizing unsaturated organosilicone compositions DOW CORNING CORPORATION (US) 1989-05-24 EP disclosed
US-4798889-A HYDROXYLAMINE, POLYMERIZATION INHIBITION DOW CORNING CORPORATION (US) 1989-01-17 US disclosed
US-4447633-A NON-AROMATIC CARBON TO CARBON PI BONDS NORTH DAKOTA STATE UNIVERSITY (US) 1984-05-08 US disclosed
US-4153765-A Curable composition containing EPM or EPDM interpolymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1979-05-08 US disclosed
US-4028483-A EPDM interpolymers formed with unsaturated organosilanes COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SLTM, SKP2, BCAT2 MAOB 3996/4885MEN1 3548/4885KMT2A 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.