SCHEMBL8090798

SCHEMBL8090798

CCCc1cccc(CC)c1CCC

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
DAO P14920 1/20 0.40
TAAR1 Q96RJ0 2/20 0.39
HTR1A P08908 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
KCNH2 Q12809 2/20 0.36
SCN5A Q14524 2/20 0.36
TSHR P16473 1/20 0.36
IAPP P10997 1/20 0.35
CACNA1C Q13936 1/20 0.35
ELANE P08246 1/20 0.35
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597268 0.95 GABRA1 (0.50) GABRA1GABRB2DAOTAAR1HTR1A
SCHEMBL1452942 0.93 ALDH1A1 (0.41) GABRA1GABRB2DAOKDM4EALDH1A1
SCHEMBL3679615 0.91 GABRA1 (0.46) GABRA1GABRB2DAOTAAR1HTR1A
Water SCHEMBL27861171 0.88 GABRA1 (0.44) GABRA1GABRB2DAOTAAR1HTR1A
Benzene SCHEMBL10959902 0.88 GABRA1 (0.44) GABRA1GABRB2DAOTAAR1HTR1A
Hydrogen Peroxide SCHEMBL28975560 0.86 GABRA1 (0.48) GABRA1GABRB2DAOTAAR1HTR1A
SCHEMBL9046269 0.84 GABRA1 (0.38) GABRA1GABRB2DAOTAAR1HTR1A
SCHEMBL18243276 0.84 GABRA1 (0.39) GABRA1GABRB2DAOLTB4RLTB4R2
SCHEMBL9447628 0.84 LIPG (0.42) KDM4ELTB4RLTB4R2KCNH2
SCHEMBL2697180 0.82 GABRA1 (0.43) GABRA1GABRB2DAOTAAR1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed
US-5202516-A Transalkylating benzene with mixture of alkylbenzenes using acidic mordenite zeolite catalyst; separating trialkylbenzene isomers using dealuminated zeolite Y adsorbent THE DOW CHEMICAL COMPANY (US) 1993-04-13 US disclosed