Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084726 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL9322653 | 0.90 | ALDH1A1 (0.56) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL653527 | 0.89 | ALDH1A1 (0.67) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL29402682 | 0.89 | ALDH1A1 (0.67) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL7072231 | 0.86 | ALDH1A1 (0.69) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL3319482 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL7542537 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL16166065 | 0.83 | ALDH1A1 (0.62) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL6055692 | 0.83 | ALDH1A1 (0.62) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 | |
| SCHEMBL7793677 | 0.83 | ALDH1A1 (0.62) | ALDH1A1CYP3A4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831081-B1 | Production of aminophenols | CIBA SC HOLDING AG (CH) | 2000-11-02 | — | — | EP | disclosed |
| EP-0831081-A1 | Production of aminophenols | Ciba SC Holding AG (CH) | 1998-03-25 | — | — | EP | disclosed |