SCHEMBL9322653

SCHEMBL9322653

CCCCN(CC(C)C)c1cccc(O)c1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 1/20 0.56
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
HTR7 P34969 3/20 0.45
OPRM1 P35372 8/20 0.43
OPRD1 P41143 7/20 0.43
OPRK1 P41145 7/20 0.43
DRD2 P14416 4/20 0.43
DRD3 P35462 4/20 0.43
TSHR P16473 1/20 0.43
DRD1 P21728 1/20 0.39
DRD4 P21917 1/20 0.39
DRD5 P21918 1/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8090933 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL653527 0.87 ALDH1A1 (0.67) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL29402682 0.87 ALDH1A1 (0.67) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL6908896 0.85 ALDH1A1 (0.63) ALDH1A1CYP3A4HTR7OPRM1OPRD1
SCHEMBL9304794 0.84 ALDH1A1 (0.73) ALDH1A1CYP3A4HTR7OPRM1OPRD1
SCHEMBL7074346 0.84 ALDH1A1 (0.73) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL3319482 0.82 ALDH1A1 (0.65) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL7542537 0.81 ALDH1A1 (0.59) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL16166065 0.81 ALDH1A1 (0.62) ALDH1A1CYP3A4NR1H2NR1H3HTR7
SCHEMBL7793677 0.81 ALDH1A1 (0.62) ALDH1A1CYP3A4NR1H2NR1H3HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4001161-A None JP disclosed
EP-0410206-B1 Fluoran compounds, crystalline toluene adducts thereof, recording material comprising same and process for their preparation MITSUI TOATSU CHEMICALS (JP) 1994-09-28 EP disclosed
US-5324704-A Supported chromogen layers for pressure or heat sensitive recording sheets MITSUI TOATSU CHEMICALS, INC. (JP) 1994-06-28 US disclosed
US-5220038-A FLUORAN COMPOUNDS, CRYSTALLINE TOLUENE ADDUCTS THEREOF, RECORDING MATERIAL COMPRISING SAME AND PROCESS FOR THEIR PREPARATION MITSUI TOATSU CHEMICALS, INC. (JP) 1993-06-15 US disclosed
JP-H041161-A 3-AMINOPHENOL DERIVATIVE AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1992-01-06 JP disclosed
EP-0410206-A1 Fluoran compounds, crystalline toluene adducts thereof, recording material comprising same and process for their preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-01-30 EP disclosed