Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 3/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902337 | 0.89 | NR1D1 (0.42) | NR1D1LDHAMMP1CACNA1BL3MBTL1 | |
| SCHEMBL8668171 | 0.89 | ACACB (0.37) | NR1D1PPARGPPARA | |
| SCHEMBL8091529 | 0.89 | CTSS (0.39) | NR1D1OPRM1OPRD1OPRK1 | |
| SCHEMBL8099090 | 0.89 | SMN1; SMN2 (0.44) | NR1D1ALDH1A1 | |
| SCHEMBL8671108 | 0.84 | ACACB (0.40) | NR1D1PPARGPPARA | |
| SCHEMBL15044629 | 0.83 | ACACB (0.38) | NR1D1ATMALDH1A1 | |
| SCHEMBL92706 | 0.83 | ACACB (0.38) | NR1D1ATMALDH1A1 | |
| SCHEMBL7516386 | 0.83 | PTPN1 (0.41) | NR1D1SIGMAR1 | |
| SCHEMBL5374479 | 0.83 | CTSS (0.38) | NR1D1OPRM1OPRD1OPRK1 | |
| SCHEMBL8391033 | 0.82 | NR1D1 (0.46) | NR1D1LDHAMMP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6039931-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5798092-A | METAL COMPLEXES; CONTRAST AGENTS FOR MEDICAL IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-25 | — | — | US | disclosed |
| US-5695739-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0405704-B1 | DTPA-complexes derivatives, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0405704-A2 | DTPA-complexes derivatives, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-02 | — | — | EP | disclosed |