Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535890 | 0.87 | SLC13A5 (0.44) | SLC13A5FFAR1FFAR2FFAR4VDR | |
| SCHEMBL8747124 | 0.83 | TSHR (0.54) | VDRALDH1A1KDM4ELMNAGAA | |
| SCHEMBL6086103 | 0.78 | FFAR1 (0.46) | FFAR1FFAR2FFAR4VDRCYP19A1 | |
| SCHEMBL4238030 | 0.78 | ESR1 (0.55) | VDRALDH1A1CYP2C19HIF1A | |
| SCHEMBL29690460 | 0.78 | ESR1 (0.55) | VDRALDH1A1CYP2C19HIF1A | |
| SCHEMBL3753644 | 0.78 | AKR1C3 (0.49) | FFAR1FFAR2FFAR4VDRCYP19A1 | |
| SCHEMBL8647874 | 0.78 | VDR (0.44) | VDRCYP19A1KDM4EGAATAS1R3 | |
| SCHEMBL8091112 | 0.76 | ALDH1A1 (0.51) | ALDH1A1LMNAHSD17B10CYP2C19HIF1A | |
| SCHEMBL16276503 | 0.76 | VDR (0.45) | VDRCYP19A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21350347 | 0.75 | CA12 (0.50) | SLC13A5ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862550-B1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0862550-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997009294-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | disclosed |