SCHEMBL8747124

SCHEMBL8747124

COc1cc(C(C)(CC(=O)O)c2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
GAA P10253 4/20 0.54
ALDH1A1 P00352 2/20 0.54
NFKB1 P19838 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
HTT P42858 2/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
SLC22A8 Q8TCC7 1/20 0.47
RAB9A P51151 1/20 0.47
CHEK1 O14757 1/20 0.46
FYN P06241 1/20 0.46
PDGFRB P09619 1/20 0.46
PIM1 P11309 1/20 0.46
FGFR1 P11362 1/20 0.46
FLT1 P17948 1/20 0.46
GRK5 P34947 1/20 0.46
MAP2K2 P36507 1/20 0.46
MAPK8 P45983 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8090992 0.83 SLC13A5 (0.44) GAAALDH1A1KDM4EHSD17B10CYP2C19
SCHEMBL16649199 0.80 MAOB (0.50) TSHRGAAALDH1A1NFKB1TDP1
SCHEMBL29690460 0.80 ESR1 (0.55) ALDH1A1CHEK1FYNPDGFRBPIM1
SCHEMBL4238030 0.80 ESR1 (0.55) ALDH1A1CHEK1FYNPDGFRBPIM1
SCHEMBL27181142 0.79 HTT (0.54) TSHRGAAALDH1A1NFKB1TDP1
SCHEMBL17273178 0.78 CHEK1 (0.49) TSHRGAAALDH1A1NFKB1TDP1
SCHEMBL31070029 0.78 HTT (0.53) TSHRGAAALDH1A1NFKB1TDP1
SCHEMBL29357116 0.78 CHEK1 (0.48) ALDH1A1TDP1HTTCHEK1FYN
SCHEMBL8747243 0.78 CA2 (0.49) TSHRALDH1A1HTTCHEK1FYN
SCHEMBL2801169 0.78 CHEK1 (0.48) ALDH1A1TDP1HTTCHEK1FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP claimed
US-5384303-A Heat sensitive elements for color images with stabilizers NEW OJI PAPER CO., LTD. (JP) 1995-01-24 US claimed
EP-0535788-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
EP-0535788-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-03-05 EP disclosed
US-5384303-A Heat sensitive elements for color images with stabilizers NEW OJI PAPER CO., LTD. (JP) 1995-01-24 US disclosed
EP-0535788-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP disclosed