Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL8097570 | 0.90 | MEN1 (0.88) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL21677 | 0.90 | MEN1 (0.95) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL680531 | 0.88 | L3MBTL1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| Hydrochloric Acid SCHEMBL6552954 | 0.88 | MEN1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| Dimethylamine SCHEMBL28184834 | 0.88 | L3MBTL1 (0.63) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL19391367 | 0.86 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL920070 | 0.86 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL9149422 | 0.86 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL15766433 | 0.86 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL5911099 | 0.86 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057371-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS, DRUG ABUSE, ANGINA, MIGRAINE, HYPERTENSION AND DEPRESSION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2000-05-02 | — | — | US | claimed |
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | claimed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | claimed |