Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL7727942 | 0.83 | LMNA (0.45) | MAPTLMNAL3MBTL1 | |
| Alcohol SCHEMBL30902548 | 0.79 | ALDH1A1 (0.35) | LMNATSHR | |
| Alcohol SCHEMBL9255779 | 0.79 | — | — | |
| Propylene Glycol SCHEMBL28380393 | 0.79 | CA1 (0.52) | TDP1LMNAPIK3CDTSHR | |
| Glycerin SCHEMBL2231098 | 0.77 | ALDH1A1 (0.39) | LMNA | |
| Alcohol SCHEMBL5583859 | 0.77 | ALDH1A1 (0.33) | LMNATSHR | |
| Propylene Glycol SCHEMBL9346240 | 0.77 | TDP1 (0.39) | TDP1 | |
| Ethylene Glycol SCHEMBL14167836 | 0.76 | TSHR (0.35) | LMNATSHR | |
| Lactic Acid SCHEMBL28865699 | 0.76 | TP53 (0.52) | L3MBTL1TSHR | |
| Methyl Alcohol SCHEMBL1326722 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050055-A2 | A POWER TRANSFORMER/REACTOR | ABB AB (SE) | 2000-11-08 | — | — | EP | claimed |
| WO-1999028927-A2 | A POWER TRANSFORMER/REACTOR | ABB AB (SE) | 1999-06-10 | — | — | WO | claimed |
| WO-2023093468-A1 | WATER CONTENT AND DENSE STATE REGULATION AND CONTROL METHOD BASED ON WEATHER-RESISTANT HYDROGEL ROADBED OPERATION PERIOD | 山东交通学院 | 2023-06-01 | — | — | WO | disclosed |
| CN-114032723-B | Method for regulating and controlling water content and compact state of roadbed based on weather-resistant hydrogel in operation period | 山东大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114032723-A | Method for regulating and controlling water content and compact state of roadbed based on weather-resistant hydrogel in operation period | 山东大学 | 2022-02-11 | — | — | CN | disclosed |